May 25, 2022 by Susan B Racette, Valene Garr Barry, Connie W Bales, Megan A McCrory, Kathleen A Obert, Cheryl H Gilhooly, Susan B Roberts, Corby K Martin, Catherine Champagne, Sai Krupa Das

Associations between the timing of eating and weight-loss in calorically restricted healthy adults: Findings from the CALERIE study

May 20, 2022 by Jason G Fleischer, Sai Krupa Das, Manjushri Bhapkar, Emily N C Manoogian, Satchidananda Panda

Challenges in defining successful adherence to calorie restriction goals in humans: Results from CALERIE™ 2

March 07, 2022 by Corby K Martin, Christoph Höchsmann, James L Dorling, Manjushri Bhapkar, Carl F Pieper, Susan B Racette, Sai Krupa Das, Leanne M Redman, William E Kraus, Eric Ravussin , CALERIE™ Phase 2 Study Group

The Complicated Relationship between Dieting, Dietary Restraint, Caloric Restriction, and Eating Disorders: Is a Shift in Public Health Messaging Warranted?

January 18, 2022 by Tiffany M Stewart, Corby K Martin, Donald A Williamson

Calorie restriction improves lipid-related emerging cardiometabolic risk factors in healthy adults without obesity: Distinct influences of BMI and sex from CALERIE™ a multicentre, phase 2, randomised controlled trial

January 18, 2022 by Kim M Huffman, Daniel C Parker, Manjushri Bhapkar Susan B Racette, Corby K Martin, Leanne M Redman, Sai Krupa Das, Margery A Connelly, Carl F Pieper Melissa Orenduff, Leanna M Ross, Megan E Ramaker, James L Dorling, Clifford J Rosen Irina Shalaurova James D Otvos Virginia B Kraus, William E Kraus, CALERIE™ Investigators

A toolkit for quantification of biological age from blood chemistry and organ function test data: BioAge

November 08, 2021 by Dayoon Kwon, Daniel W Belsky

Association between the FTO rs9939609 single nucleotide polymorphism and dietary adherence during a 2-year caloric restriction intervention: Exploratory analyses from CALERIE™ phase 2

September 28, 2021 by James L. Dorling, Daniel W. Belsky, Susan B. Racette, Sai Krupa Das, Eric Ravussin, Leanne M. Redman, Christoph Höchsmann, Kim M. Huffman, William E. Kraus, Michael S. Kobor, Julia L. MacIsaac, David T.S. Lin, David L. Corcoran, Corby K. Martin

Effect of 2-year caloric restriction on organ and tissue size in nonobese 21- to 50-year-old adults in a randomized clinical trial: the CALERIE study

June 28, 2021 by Wei Shen, Jun Chen, Jane Zhou, Corby K Martin, Eric Ravussin, Leanne M Redman

Beyond weight loss: current perspectives on the impact of calorie restriction on healthspan and lifespan

May 10, 2021 by Maryam Kebbe, Joshua R Sparks, Emily W Flanagan, Leanne M Redman

Funding Opportunities

Calerie Centers

Publications

Principal component-based clinical aging clocks identify signatures of healthy aging and targets for clinical intervention

Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT

Calorie restriction reduces biomarkers of cellular senescence in humans

Calorie restriction modulates the transcription of genes related to stress response and longevity in human muscle: The CALERIE study

Body shape perception in men and women without obesity during caloric restriction: a secondary analysis from the CALERIE study

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial.

No Effect of Calorie Restriction or Dietary Patterns on Spatial Working Memory During a 2-Year Intervention: A Secondary Analysis of the CALERIE Trial

Epigenome-wide association study analysis of calorie restriction in humans, CALERIE™ Trial analysis

No Effect of Calorie Restriction or Dietary Patterns on Spatial Working Memory During a Two-Year Intervention: A Secondary Analysis of the CALERIE Trial

Modestly Increased Incidence of Ketosis in Caloric Restriction Does not Significantly Alter the Effects of Caloric Restriction

Nutritional quality of calorie restricted diets in the CALERIE™ 1 trial